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ANTIBODY-DEPENDENT ENHANCEMENT
Descriptors Found:
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DeCS
Descriptor
English
:
Antibody-Dependent Enhancement
Descriptor
Spanish
:
Acrecentamiento Dependiente de Anticuerpo
Descriptor
Portuguese
:
Anticorpos Facilitadores
Tree Number:
G06.590.875.040
G06.920.875.040
G12.425.040
Definition
English
:
Enhancement of viral infectivity caused by non-neutralizing
antibodies
. There are at least two mechanisms known to account for this: mediation by
Fc receptors
(RECEPTORS, FC) or by
complement receptors
(RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral
IMMUNOGLOBULIN G
and binds to
Fc receptors
, or virus is coated with antiviral
IMMUNOGLOBULIN M
and binds to
complement receptors.
Indexing Annotation
English
:
enhancement of viral infectivity: read MeSH definition
History Note
English
:
96
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
32854
Unique Identifier:
D019067
Occurrence in VHL
:
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